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Action Mechanism of Sildenafil Citrate

Erectile dysfunction is a disorder which is denoted by loose or no erection in the male organ. Reduced blood flow to the male organ causes erectile failure in men. It develops under the influence of an enzyme known as phosphodiesterase type 5 or PDE5. Proper blood provision to the male organ creates stiffer and harder erection at the time of copulation.

Sildenafil citrate belongs to the PDE5 blocker group of drugs. Cyclic guanosine monophosphate or cGMP is responsible for the relaxation of smooth muscles of blood vessels. It results in increases amount of blood flowing to the male organ. Nitric oxide binds with the guanylate cyclase receptor and this union increases the amount of cGMP in the male organ. This causes relaxation of smooth muscles and increase in the blood provision to the male organ. PDE5 affects cGMP levels in the male reproductive system thus affecting erection process.

Sildenafil citrate 200mg tablet when taken, interferes with the action of PDE5 over cGMP levels. Once the action of this enzyme is cut down, blood vessels relax and become wide enough to carry abundant of blood to the male organ causing erection. It stays intact for around four hours

Precautions

  • One may develop allergic reactions with sildenafil citrate. If it happens then it is better to discontinue using this medicine. Consult a doctor if symptoms persist.
  • People suffering with health issues such as kidney disorders, liver problems and heart diseases shouldn´t take this medicine. Consuming anti-impotence medications may worsen these health concerns and thus one must consult a doctor before going ahead with this drug.
  • Sildenafil citrate is made for men with erectile discomfort. Women and children are prohibited to consume this drug.
  • Dizziness is one of the side effects of this medicine. Thus after having this drug one must avoid doing work that requires alertness. Avoid driving a car or operating machinery.
  • Water is the best liquid to consume drug with. Avoid having it with booze or grapefruit juice. This combination affects health of the consumer.
  • Heart patients taking nitrate drugs shouldn´t buy sildenafil citrate pills. Combining anti-impotence drugs with nitrate medicines creates negative effects on the health of heart.
  • If you experience painful erection or it stays longer than four hours then you must get immediate medical treatment.
  • This anti-impotence medication saves one from erection trouble but it doesn´t provide protection from sexually transmitted diseases or STDs and HIV infection.

Dosage

Accurate dosage leads to better outcome. Sildenafil citrate pills are available in various strengths. You can either take 25mg, 50 mg or 100mg pills as it depends on the severity of your problem and also how your body responds to the medication. Take the pill as a whole without breaking or crushing it. It may reduce its effectiveness. It is better to consume the drug on an empty stomach as it initiates faster absorption thus giving excellent results. Sildenafil citrate 100mg is the ideal dosage that suits almost every sufferer. Avoiding alcohol and grapefruit juice is the best way to keep health complications at bay.

Side Effects of Sildenafil Citrate 200mg

Every medicine causes some negative effects which are termed as side effects. These are mandatory to develop as their appearance indicates that our body is adjusting with the medicine. With sildenafil citrate pills, you also get side issues which are normally gentle in nature thus do not cause any complication. But in rare cases, severe effects have been observed with this medicine. Ask your doctor about aftermaths of anti-impotence drugs so that you can deal with them in better ways once they occur.

There are mild side effects with sildenafil citrate which includes upset stomach, headache, facial reddening, stuffy or runny nose and nauseated feeling. These are harmless effects and don´t bother the sufferer. These after effects vanish within couple of days and if they don´t then you need to call on medical help. It is better to consult a doctor if these aftermaths become severe in nature. Follow the precautions or safety measures properly to keep complications at bay.

Incidents are very rare that one get severe effects because of sildenafil citrate 200mg consumption. This strength is effective and well tolerated by men. But if it is giving you bothersome side issues then you must reduce the strength and see what happens. Infrequently you may suffer from fast or irregular heartbeats and prolonged erection which is painful. In such cases getting prompt medical help is necessary.

Warnings of Sildenafil Citrate

  • This anti-impotence drug is not related to augmentation of erotic desire or libido in men. Hence it must be consumed to treat erectile dysfunction. Erotically healthy men shouldn't buy sildenafil citrate pills.
  • Women and children shouldn't have this medicine as it is not made for them. Only men suffering from erectile issues can take this drug to improve their condition.
  • Certain health issues such as heart problems, liver and kidney disorders don't allow men to consume this medicine. This may worsen the situation.
  • Anti-ED drugs may create serious side effects such as painful and prolonged erection that stays for more than four hours. In such scenario one must consult a health care provider.
  • Sildenafil citrate is only a way to get proper erection at the time of carnal activity. It won't save you from STDs or HIV infection.
  • Do not mix up your anti-impotence drugs with nitrate meds as this combination affects your heart.